Medical chemistry part-2

First discovery of drug?

 In 1820 the drug was discovered  from bark of tree

i.e. discovery of quinine. Anti malarial drug which also has antipyretic (fevar reducing) properties.upto 2006 quinine was among the first line treatment for malaria. After Modifying that structure of quinine many  drugs are discovered. This is an Classical  example how one can use traditional methods to discover a drug.

Discovery of penicillium - Alexander Fleming.

Alexander Fleming who was microbiologist who was working with staphylococcus aureus &once during in many years working in lab he left a petri dish  containing staphylococcus. After several months once he got back he found that there was some contamination  in the Petri dish he observed that there was a family of moulds which is basically fungus is growing and that fungas was stoping the growth of staphylococcus aureus that is  subsequently identified as penicillium. It means that discovery of penicillium was accidentally. 
Similarly many life saving drugs such as cisplantin&taxil are effective in cancer therapy&Azidothymidine used for helping AIDS patients, have been isolated from plants & animals source or prepared by synthetic methods.